Sustanon 250 – Effective Dosage and Side Effects

Pharmaceutical Name: Testosterone

Chemical Structure: 4-androsten-3-one-17beta-ol, 17beta-hydroxy-androst-4-en-3-one

Delivery Method: Injectable

Half-Life: 15 – 18 days

Sustanon 250 is a blend of the testosterone containing 60 mg of testosterone phenylpropionate, testosterone isocaproate, and testosterone decanoate each. It is popular among the bodybuilders due to its long half-life. Individuals that are injected with compound are able to maintain stable levels for a long period without needing to constantly pin themselves with a needle. The steroid was manufactured for the treatment of low testosterone levels in males. The idea behind the injectable steroid was to offer the best of small and long ester testosterone that requires infrequent injection and offers fast acting results.

Administration of Sustanon 250

The standard dosage Sustanon 250 dosage is 500 mg per week for twelve weeks. However, individuals that suffer from constant low testosterone level can use the steroid indefinitely. Around 250 mg per week is suitable for continual treatment of low testosterone either due to natural causes or due to the use of anabolic steroids.

Most men report significant results when using 750 – 1,000 mg every week. While higher testosterone levels produce noticeable results, it also increases the chances of side effects associated with the steroid drug. The extent of the side effects experienced by an individual will differ from one individual to the next. However, doses above 1,000 mg per week greatly increase the likelihood of negative side effects.

One of the best things about Sustanon 250 is that it stacks well with all kinds of anabolic steroids. You can use it in place of any testosterone base. Below we have listed the cycles for off-season bulking and preseason cutting cycles.


Sustanon Cycles
A. Off-season Bulking - Total length = 12 weeks
Weeks 1-12
·        Arimidex 0.5 mg alternate days
·        Sustanon 250 500 mg per week
Weeks 1-6
·        Dianabol 25 mg per day
B. Pre-season Cutting Cycle - Total length = 12 weeks
Weeks 1-12
·        Letrozole 0.5 mg alternate days
·        Sustanon 250  500 mg per week
Weeks 5-12
·        Anavar 50 mg per day

Side Effects of Sustanon

Keep in mind that some people find Sustanon 250 painful to administer. The reason is that it contains propionate ester that feels irritating to certain individuals. In such a situation, it’s recommended to use a testosterone steroid that can be injected orally.

Sustanon 250 is relatively well tolerated by most healthy males. Most of the side effects are minor and controllable. The chances of experienced side effects depend on the genetic predispositions of the individual. However, generally, it is a safe supplement for the majority of bodybuilders.

The side effects will be little to none for individuals that are using the steroids for treating low testosterone levels.

Bodybuilders that use the steroid to boost testosterone levels should apply caution and use it according to the recommended dosage instructions. While most men can tolerate higher dosages, but there is generally a cutoff point (normally 1,000 mg) after which the likelihood of side effects increases significantly. That being said, the cutoff point also varies from one individual to the next. Below are some of the side effects that are commonly encountered by individual taking Sustanon 250 for long periods and/or high dosages.

Estrogenic Effects

The testosterone compounds present in Sustanon 250 will react in the system in a similar manner to the administration of other steroids. The increase in the testosterone levels will increase the chances of development of estrogen, which results in a number of other complications such as water retention, acne, hair loss, and gynecomastia.

Water Retention

Sustanon 250 ingredients can cause muscles to hold more intracellular and extracellular water. This results when testosterone reacts with aromatase enzyme the lead to the formation of estrogen. Increased levels of this hormone cause the body to retain water and sodium, which creates an imbalance in the body’s electrolyte levels.

Individuals can remedy the water retentions issues by using an aromatase inhibitor (AI). The AI inhibits aromatase in retaining water in the body. The typical dosage of AI would be around 5 mg twice a day or 10 mg every day. Moreover, you can also solve the water retention problem by switching to a low cardio and sodium diet.


Increased estrogen levels in the body also results in the formation of acne. A remedy to this problem is to use AI. You can also consider taking Accutane at 10 to 20 mg per day in order to prevent the buildup of acne. Remember to take the medications according to recommended instructions as it can lead to liver and kidney problems.


The condition of gynecomastia occurs when the breast tissues grow around the nipple in males. Increased level of estrogen can result in the appearance of full grown breasts in males. The condition can be cured by reducing the estrogen levels in the body. As discussed above, you can use AI to reduce the estrogenic effects that occur due to increased level of testosterone in the body. In addition, Selective Estrogen Receptor Modulators (SERM) can be used to block development of the breast tissue. The drug will prevent the growth of breast tissues around the nipple. The treatment plan should be used by individuals that are having difficulty with AI.  Also, a surgery can be performed in case the medications do not help in remedying the problem.


Hypertension is common among people that use anabolic steroids. Also known as high blood pressure, it usually occurs due to long-term use and/or higher dosages. The condition develops due to building up of sodium in the body. The sodium retention rates can be controlled by switching to low carb and low sodium diet. Moreover, usage of the steroid drug results in a reduction in high-density lipoprotein (HDL) and increase in the harmful low-density lipoprotein (LDL) that ultimately leads to high blood pressure.



Sustanon 250 can also lead to the hypothalamic pituitary testicular axis (HPTA) particularly when it’s not used according to recommended dosage instructions. This occurs to increased level of testosterone in the body.

Enlarged Prostate

Another serious side effect of taking Sustanon 250 is enlarged prostate - a dangerous side effect increases the chances of prostate cancer formation. Controlling 5-alpha inhibitors and DHT helps by using drugs like Finasteride can help in controlling the negative effects of prostate enlargement.