Effective Dosage and Side Effects of Anadrol Steroids

Pharmaceutical Name: Oxymetholone

Chemical Structure: 17β-hydroxy-2-hydroxymethylene-17-methyl-5α-androstan-3-one

Delivery Method: Injectable

Half-Life: 8 – 9 hours

Developed in 1959, Anadrol is one of the most effective anabolic steroids.,. It is used in the treatment of a number of medical conditions including muscular atrophy, debilitating geriatric conditions, osteoporosis, anemia, and catabolic medical condition. The medication is also used for weight gain and preservation of mass during treatments.

Being a modified variant of Dihydrotestosterone (DHT), Anadrol is super effective in gaining muscle mass. The anabolic steroid is a DHT with a methyl group attached to it that provides greater oral bioavailability. It belongs to the 2- hydroxymethylene group that is bonded to the carbon atom of DHT’s cycloalkane ring. The chemical properties allow the steroid to be extremely resistant to metabolic breakdown due to which a small dose of the medication results in greater cellular activity leading to muscle gain. Moreover, it does not interact with aromatase enzyme that is responsible for the production of estrogen in the body and presence of which leads to different complications.

In addition, Anadrol being a DHT derivative does not interact with the 5-alpha reductive enzyme that reduces the potential androgenic effects. It is a type of an artificial hormone similar to testosterone but with greater potency.

Administration of Anadrol

Initially, the recommended dose of Anadrol was 2.5 mg administered three times a day. However, later on, the standard dose of the steroid medication increased due to change in the approved medical conditions for Anadrol. Today, the suggested dose of the drug is 1 – 5 mg per body weight measured in kilogram. So, for individuals with a body weight of 85 kg, the recommended dosage ranges from 85 mg to 425 mg per day.

Due to the chances of development of liver toxicity problems, it is suggested that the steroid should not be administered for more than 4 – 6 weeks at a time. It’s best to use the drug in cycles. Anadrol is relatively restrictive in the sense that it can be stacked in cycles with only a few anabolic steroids. Below is the suggested cycle for Anadrol that offers maximum benefits for bodybuilders to gain muscle mass.

Anadrol Cycles
A. Novice Cycle – Total length = 12 weeks
Weeks 1-12
·        Testosterone (Enanthate/ Sustanon/ Cypionate) 300 – 500 mg per week
Weeks 1-6
·        Anadrol 25 – 50 mg per day
 
B. Intermediate Cycle – Total length = 12 weeks
Weeks 1-12
·        Testosterone (Enanthate/ Sustanon/ Cypionate) at 100 mg per week
·        Deca-Durabolin (Nandrolone Decanoate) at 400 mg per week
Weeks 1-6
·        Anadrol at 50 mg per day
 
C. Advanced Cycle – Total length = 8 weeks
Weeks 1-8
·        Testosterone Propionate at 100 mg per week (25 mg alternate days)
·        Trenbolone Acetate at 400 mg per week (100 mg alternate days)
Weeks 1-6
·        Anadrol at  100 mg per day

 

Side Effects of Anadrol

Anadrol is a DHT derivative that has been altered at the 17th carbon position. Due to this fact, it is known as a 17-Alpha-Alkylated steroid. This property of the steroid drug makes it suitable for oral ingestions. However, a major downside with the anabolic steroid is that it is very taxing on the liver. Apart from that, there are other side effects associated with the drug as mentioned below.

Androgenic effects

The androgenic side effects are less severe with Anadrol as compared to testosterone. However, this does not rule out that the effects do not happen. While most of the people do not experience any androgenic effects, some people have reported pronounced effects such as bodily and facial growth, increased sebum secretion, greater bouts of acne, and increased the incidence of Male Pattern Baldness (MPB) particularly in individuals that are predisposed to the condition.

Estrogenic effects

The use of Anadrol does not lead to the production of estrogen. However, Anadrol in itself acts as an estrogen. For the same gynecomastia that is one of the estrogenic side effects, reason cannot be treated using  aromatase inhibitors (AI). The only treatment for the condition is the use of Selective Estrogen Receptor Modulators (SERMs) such as Nolvadex.

Other estrogenic effects that occur due to long-term or high dosage of the anabolic steroid include water retention and the resultant increased blood pressure, and a possible increased retention of fat. Also, the water retention problem cannot be treated through dietary changes as is the case when taking other types steroids.

Hepatotoxic effects

Hepatotoxic is another side effect that is associated with the use of Anadrol. Excessive dosage of the anabolic steroids leads to serious health complication complications including the development of life-threatening tumors.

Cardiovascular effects

Anabolic steroids lead to negative cardiovascular effects. The same is the case with Anadrol. Large doses of the medication can lead to decreased levels of high-density lipoprotein (HDL) and reduced levels of low-density lipoprotein (LDL). Changes in the cholesterol profile lead high blood pressure that leads to increased risk of cardiovascular complications such as heart attack and stroke.

Also, hepatotoxic side effect tends to worsen cardiovascular health. The reason is that liver generates enzymes that control cholesterol levels in the body. Increased toxicity level due to over dosage of the steroid medication leads to serious heart conditions.

HPTA suppression

A serious side effect associated with Anadrol is Hypothalamic pituitary testicular axis (HPTA) that leads to suppression of testosterone production in the body. Long term usage of the steroid may lead to the shutdown of the male hormone due to which the individual may have to rely on testosterone injections for the rest of the life. That’s what it is essential to take proper precautions when taking the anabolic steroid to gain muscle mass. It’s recommended to follow Post cycle therapy (PCT) protocol after the end of a 4-6 weeks cycle by use of testosterone-stimulating compounds such as Nolvadex.